coronavirus Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from the Hong Kong cohort and systematic review and meta-analysis. Notably, increased levels of IL-6, IL-2, IL-7, IL-10, granulocyte colony-stimulating factor (G-CSF), IP-10, MCP1, IFN, macrophage inflammatory protein 1 (MIP1), and tumor necrosis factor (TNF) have all been implicated in COVID-19 severity, suggesting a combined T-helper type 1 (Th1) and Th2 cell response (61, 130). SARS and MERS: recent insights into emerging coronaviruses. Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, Ng PC, Lam PWY, Ho LC, To WWK, Lai ST, Yan WW, Tan PYH. Su H, Yang M, Wan C, Yi LX, Tang F, Zhu HY, Yi F, Yang HC, Fogo AB, Nie X, Zhang C. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Hosier H, Farhadian SF, Morotti RA, Deshmukh U, Lu-Culligan A, Campbell KH, Yasumoto Y, Vogels CBF, Casanovas-Massana A, Vijayakumar P, Geng B, Odio CD, Fournier J, Brito AF, Fauver JR, Liu F, Alpert T, Tal R, Szigeti-Buck K, Perincheri S, Larsen CP, Gariepy AM, Aguilar G, Fardelmann KL, Harigopal M, Taylor HS, Pettker CM, Wyllie AL, Dela Cruz CS, Ring AM, Grubaugh ND, Ko AI, Horvath TL, Iwasaki A, Reddy UM, Lipkind HS. Received 2020 Jun 23; Revised 2020 Jul 7; Accepted 2020 Jul 7. coagulation, COVID-19, cytokine storm, multisystem organ failure, pathophysiolog. M.K.B. Can COVID-19 in pregnancy cause preeclampsia? and transmitted securely. However, no consistent trend in lymphocyte count was reported (56). Vaira LA, Salzano G, Fois AG, Piombino P, De Riu G. Potential pathogenesis of ageusia and anosmia in COVID-19 patients. As such, the neutrophil-to-lymphocyte ratio appears to be a useful indicator of disease prognostication and management (83). link.springer.com. Gadiparthi C, Bassi M, Yegneswaran B, Ho S, Pitchumoni CS. Hoffmann M, Kleine-Weber H, Schroeder S, Krger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu NH, Nitsche A, Mller MA, Drosten C, Phlmann S. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Impact of sex and gender on COVID-19 outcomes in Europe, Maternal and neonatal response to COVID-19. This paper proposes a model algorithm based on convolutional neural network combined with attention mechanism to realize fast and accurate identification of biological image.
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